September 2014

A recent meta-analysis of studies of the utility of the Mallampati score in the prediction of a difficult airway found that it had a sensitivity of 60% and a specificity of 70%.
  • a)  Outline what is meant by meta-analysis and the factors that ensure a high quality conclusion from the
    process. (10 marks)
  • b)  Explain what is meant by sensitivity and specificity as applied to the interpretation of the Mallampati data
    given above. (6 marks)
  • c)  Rank the levels of scientific proof used to grade medical evidence. (4 marks)
  • Pass Rate 72.8%
    It was anticipated that candidates would find this subject matter to be difficult. Surprisingly the question generated the highest overall pass rate, and the majority of candidates scored in excess of the pass mark. Weak candidates were unable to indicate how a high quality conclusion can be ensured from a meta- analysis or to interpret the data for Mallampati studies in a meaningful way.
September 2009

A recent meta-analysis of the Mallampati examination found that it had a sensitivity of about 60% and a specificity of about 70%.

a) Rank the levels of scientific proof used to grade medical evidence. (25%)

b) Explain what is meant by meta-analysis and which parameters ensure a high quality process? (25%)

c) Explain what is meant by the statistical terms:
i) sensitivity (20%)
ii) specificity (20%)
Question11 Critical care/management of airway problem/tracheostomy

76.6% pass rate

In the main was a well-answered question
October 2008

Describe how you would design and conduct a prospective randomised study to investigate whether surgical face-masks worn in theatre by medical and nursing staff prevent postoperative wound infections.

Include:
a. Study design (40%),
b. Outcomes to be measured (20%),
c. Plan of analysis (15%),
d. Advantages and limitations (15%).
Question11 Critical care/management of airway problem/tracheostomy

76.6% pass rate

In the main was a well-answered question
October 2006

(a) What are the main types of studies that must be done on a drug in order to obtain marketing authorisation (formerly called a product licence) from the Medicines and Healthcare products Regulatory Agency (MHRA)? (25%)
(b) Define what is meant by ‘a double blind randomised controlled trial with adequate power’, and explain the reasons for these methods? (50%)
(c) Under what circumstances might an observational study be an acceptable method of investigation?(15%)

Question11 Critical care/management of airway problem/tracheostomy

76.6% pass rate

In the main was a well-answered question
May 2003

What is evidence-based medicine? How would you apply the process to your clinical practice?
Question11 Critical care/management of airway problem/tracheostomy

76.6% pass rate

In the main was a well-answered question
April 2002

What is meta-analysis? Outline the methodology. How are the results usually presented?
Question11 Critical care/management of airway problem/tracheostomy

76.6% pass rate

In the main was a well-answered question